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Cisplatin (сis-Dichlorodiammine Platinum (II))

CAS-number: 15663-27-1

Chemical formula: cis-Pt(NH3)2Cl2

Metal content: ≥64.5%

Application: antineoplastic agent.

Shelf life: 2 years.

Package: dark glass jars with polyethylene caps.

 

IndicatorsTrial Data Results
AppearanceYellow-orange-coloured crystalline powder
SolubilitySlowly and very low-soluble in 0.1N HCl and 0.9% NaCl, practically insoluble in 95% alcohol
Identification: 
UV-spectrum

Max. at l=301±2 nm,
Minimum at l=246±2 nm,
Shoulder 276-284 nm

platinum qualitative testPositive
ammonia qualitative testPositive
chlorides qualitative testPositive
Solution transparencyConforms to reference standard No. 1 (National Pharmacopeia, Vol. XI)
Water, %Max. 0.5
Foreign impurities, %: 
trans-isomerMax. 1.0
other foreign impuritiesMax. 1.0
Quantitative assay, %: 
based on platinum assay resultsMin. 99.0
based on nitrogen assay resultsMin. 99.0
Platinum content, %Min. 64.35